Polysialic Acid Modulates the Binding of External Lactoferrin in Neutrophil Extracellular Traps
نویسندگان
چکیده
منابع مشابه
Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation
Neutrophils are central players in the innate immune system. They generate neutrophil extracellular traps (NETs), which protect against invading pathogens but are also associated with the development of autoimmune and/or inflammatory diseases and thrombosis. Here, we report that lactoferrin, one of the components of NETs, translocated from the cytoplasm to the plasma membrane and markedly suppr...
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Neutrophils are involved in numerous immunological events. One mechanism of neutrophils to combat pathogens is the formation of neutrophil extracellular traps (NETs). Thereby, neutrophils use DNA fibers to form a meshwork of DNA and histones as well as several antimicrobial components to trap and kill invaders. However, the formation of NETs can lead to pathological conditions triggering among ...
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ژورنال
عنوان ژورنال: Biology
سال: 2019
ISSN: 2079-7737
DOI: 10.3390/biology8020020